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Conference abstract Deep Breath author

Validation of an automated PVA detection algorithm

Rietveld TP, Rietveld PJ, Balakirev A, van der Ster BJP, Gommers D, Damiani LF, Smits F, van der Velde-Quist F, Endeman H, Snoep JWM, van Gent JO, van Oosten JP, Francovich JE, Goedendorp NG, Schoe A, Jonkman AH. Validation of an automated patient-ventilator asynchrony detection algorithm. ERJ Open Research. 2026;12(suppl 17):44.

Type
Conference abstract (ERS Respiratory Failure and Mechanical Ventilation, RFMV 2026)
Venue
ERJ Open Research, volume 12, supplement 17, abstract 44
Published
4 March 2026
DOI
10.1183/23120541.rfmv-2026.44
Publisher
ERS / ERJ Open Research
Deep Breath authors
Anton Balakirev — Deep Breath B.V., Rotterdam
Deep Breath labelling interface (left) and algorithm performance versus expert ground truth (right), from the ERJ Open Research abstract.
Figure 1 from the abstract: Deep Breath labelling interface, with the breath of interest in red, and Table 1 of per-asynchrony performance versus expert ground truth. Source: ERJ Open Research 12(suppl 17):44.

What this abstract is

A validation of an AI-based algorithm, named Deep Breath in the abstract, that detects multiple patient–ventilator asynchrony (PVA) types in real time: ineffective effort, reverse, double, and delayed triggering, and premature and delayed cycling.

Ventilator and esophageal-pressure (Pes) waveforms were collected from 24 ventilated patients. 5,169 breaths were labelled for PVA by three clinicians from a pool of twelve. Ground truth was majority vote or consensus. The algorithm classified the same breaths using only ventilator waveforms (no Pes).

Validation criteria were at least 0.95 specificity on normal breaths and at least 0.8 recall per PVA type. The authors reported macro recall 0.83, specificity 0.96, and F1-score 0.81. Minimum PVA recall was 0.8 (delayed triggering); normal-breath specificity was 0.97. Both met the pre-set criteria.

This is a conference abstract in an ERJ Open Research supplement, not a full original article. It is research evidence for PVA classification. It is not MDR or FDA clearance of a bedside decision-support product.

Deep Breath note

The abstract names Deep Breath as the algorithm validated for real-time detection of multiple PVA types on ventilator waveforms only (24 patients) against expert labels with esophageal pressure. Sensitivity / specificity / F1 versus those labels:

Class Sensitivity Specificity F1
Normal0.840.970.86
Ineffective effort0.890.990.84
Reverse trigger0.850.990.84
Delayed trigger0.800.970.75
Double trigger0.891.000.80
Premature cycling0.840.980.79

Publisher page: ERJ Open Research 12(suppl 17):44. DOI: 10.1183/23120541.rfmv-2026.44.

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